Lotus Notes Keyboard Shortcuts:

For every version of Lotus Notes, keyboard shortcuts are listed in the Lotus Notes Administration and User Help databases.
E.g.

In Lotus Notes Documents
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CTRL+DOWN ARROW = Move to next highlighted search word in document appearing in preview pane
CTRL+E = Edit document
CTRL+END = Move to bottom of document
CTRL+F = Find text and replace
CTRL+G = Find next occurrence of text
CTRL+HOME = Move to top of document
CTRL+P = Print selected document
CTRL+PAGE DOWN = Move to next tab in tabbed table
CTRL+PAGE UP = Move to previous tab in tabbed table
CTRL+UP ARROW = Move to previous highlighted search word in document appearing in preview pane
ESC = Move to previous linked document
F4 or TAB = Move to next unread document
LEFT ARROW = Move to previous link or object
RIGHT ARROW = Move to next link or object
SPACEBAR = Activate selected object
SPACEBAR = Expand or collapse selected section
SPACEBAR = Open selected link to document, view, or database
CTRL+LEFT ARROW = Beginning of current word
CTRL+RIGHT ARROW = Beginning of next word
END = End of line
HOME = Beginning of line
SHIFT+TAB = Previous field in a form
SHIFT+TAB = Previous row in table
TAB = Next field in a form
TAB = Next row in table

In Lotus Notes Databases
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You can use the following keyboard shortcuts for opening and closing a database, and for using database features including navigating within views, folders, and panes.
ARROW keys = Move through embedded element
CTRL+N = Create new database
CTRL+O = Open database
ENTER = Select item in embedded outline
ESCExit embedded element
ESC or CTRL+W = Close current database
F9 = Refresh current document (in Edit mode), view or workspace
MINUS (-) key = Collapse folder in embedded outline
PAGE DOWN = Move to bottom of active page
PAGE UP = Move to top of active page
PLUS (+) key = Expand folder in embedded outline
SHIFT+CTRL+F9 = Update all views in current database
SHIFT+F9 = Rebuild current document, view, workspace (must have Manager access)
SPACEBAR = Give focus to embedded element
UP and DOWN ARROW = Move through embedded outline